Search    Show all

1 People found

filters applied:


1 / 1

EMBO Member

Carlos López-Otín

University, Oviedo | Spain

EMBO 2010

Functional analysis of proteases in life and disease

Our work has focused on the functional analysis of proteases in life and disease. We have identified ~60 novel human proteases and defined new roles for these enzymes in cancer, premature aging, and other diseases. We have also developed tools for the global and evolutionary analysis of proteases in mammalian genomes and extended this information to cancer genome projects.

Keywords: Proteolysis / metalloproteases / cancer / aging / molecular medicine

Subject area(s): Genomic & Computational Biology | Molecular Medicine | Proteins & Biochemistry