EMBO Global Investigator
Cesar A. Ramirez Sarmiento
GIN 2023–2026
Pontifical Catholic University of Chile, Santiago de Chile, Chile
Evolution of metamorphic proteins & PET hydrolases
Our research group employs experimental and computational strategies to unveil the folding-function-evolution relationships of metamorphic proteins, prototypical models to understand the emergence of novel protein folds in nature, and of bacterial enzymes that hydrolyze PET, a widely used plastic that accumulates as waste in landfills and natural environments at similar rates to its production.
Keywords
Protein folding / metamorphic proteins / biocatalysis / plastic degradation / molecular evolution