Search    Show all

1 People found

filters applied:


1 / 1

EMBO Member

Charles Swanton

The Francis Crick Institute, London | United Kingdom

EMBO 2017

TRACERx – understanding cancer evolution

Our group's aim is to use the longitudinal TRACERx cancer cohorts to learn how genome instability fosters cell-to-cell variation – the substrate upon which Darwinian selection and evolution acts. Through this understanding, we hope to unravel the basis for drug resistance, develop means to stall evolution and target multiple ubiquitous clonal alterations through immune-based approaches.

Keywords: Cancer evolution / genome instability / chromosomal instability / personalised medicine / lung cancer

Subject area(s): Genome Stability & Dynamics | Genomic & Computational Biology | Molecular Medicine | Evolution & Ecology