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EMBO Young Investigator

Charlotte Scott

VIB Center for Inflammation Research (IRC), Ghent | Belgium

YIP 2023–2026

Myeloid cell heterogeneity in inflammation

My lab is focused on unravelling the functional heterogeneity of myeloid cells primarily in the liver in the context of tissue damage and inflammation. We use a variety of state-of-the-art single cell and spatial technologies including single cell/single nuclei RNA-sequencing, spatial transcriptomics and spatial lipidomics to unravel this heterogeneity and understand it in the context of the neighbouring cells and tissue signals.

Keywords: Immunology & inflammation / macrophages / liver / inflammation & tissue damage / NAFLD / fibrosis / acute & chronic injury / transcriptional regulation

Subject area(s): Cell & Tissue Architecture | Differentiation & Death | Immunology | Systems Biology