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EMBO Associate Member

Chi-Huey Wong

The Scripps Research Institute, La Jolla | United States

EMBO 2010

Chemical biology and carbohydrate-based drug discovery

Research in our lab focuses in the areas of bioorganic and synthetic chemistry, including synthesis of complex carbohydrates, glycoproteins and small-molecule probes for the study of carbohydrate-mediated biological recognition, post-translational glycosylation, and drug discovery. Our original work on programmable one-pot reactions has provided a powerful platform for use to tackle important problems in biology, especially those associated with cancer, infectious diseases and immune system.

Keywords: Carbohydrate chemistry / glycobiology / post-translational glycosylation / drug discovery / vaccine design

Subject area(s): Molecular Medicine | Proteins & Biochemistry | Structural Biology & Biophysics