Computational genomics in health and disease
My lab contributed to many landmark genome sequencing projects, but our work now focuses on disease genomics, noncoding RNA, and next-generation sequencing functional analyses. The group has predicted that 8% of the human genome is functional, demonstrated the functionality of ncRNA genes in mammals and fruitflies, and provided an online atlas of transcription for mouse cortical cell layers.
Keywords
Computational genomics / noncoding RNA / genome evolution / gene evolution / comparative transcriptomics