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EMBO Young Investigator

Christian Münch

Goethe University, Frankfurt | Germany

YIP 2022–2025

Cellular proteostasis control and stress responses

Cellular protein homeostasis (proteostasis) is under continuous strain, particularly in numerous human diseases, such as neurodegeneration, infection and cancer. My group studies the resulting stress responses in mitochondria and other cellular compartments to better understand how cells react to different stresses. We aim to understand molecular and system-wide effects to gain a comprehensive understanding of pathways, regulation and modulation.

Keywords: Proteostasis / mitochondria / protein folding / autophagy / translation / proteomics / systems biology / disease

Subject area(s): Cellular Metabolism | Proteins & Biochemistry | Signal Transduction | Systems Biology