Biozentrum, Basel | Switzerland
EMBO 2013 | YipC 16–19 | YipC 20–
My group is studying the role of type IV secretion (T4S) systems in the establishment of persistent bacterial infection. Our research focusses on structure/function analysis of T4S system-translocated bacterial effector proteins and their cellular targets. Moreover, we are employing systems biology approaches to reveal the host cell signaling network underlying bacterial cell invasion and intracellular persistence.
Keywords: Bacterial pathogenesis & persistence / secretion systems / effector proteins / cell entry / intracellular trafficking