Bacterial pathogenesis and vaccine development
My group works on the pathogenesis of infections caused by Neisseria meningitidis and Shigella flexneri. The main interests of the group are the interaction of these bacteria with the immune system, and their ability to adhere to and enter cells. The group also aims to devise approaches to prevent these infections through vaccines based on understanding the virulence mechanisms the bacteria employ to cause disease.
Keywords
Microbiology / protein structure / innate immunity / infectious diseases / serum resistance