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EMBO Member

Christopher W.J. Smith

University of Cambridge | United Kingdom

EMBO 2009

Regulation of alternative pre-mRNA splicing

My group is interested in the mechanisms that govern alternative pre-mRNA splicing decisions. We use a combination of approaches including detailed analysis of model alternative splicing systems as well as global profiling of alternative splicing. We have a particular interest in regulatory networks between splicing factors involving alternative splicing linked to nonsense-mediated decay (NMD).

Keywords: Alternative splicing / pre-mRNA splicing / RNA / RNA binding proteins / RNA processing / Nonsense Mediated Decay

Subject area(s): RNA