EMBO Member
Claes B. Wollheim
EMBO 1993
Medical Center, Geneva, Switzerland
Islet hormone regulation of glucose homeostasis
I am active emeritus and continue to be involved in research on the mechanism of pancreatic beta cell function in health and type 2 diabetes. My speciality is signal transduction and gene expression in pancreatic islet alpha and beta cells as well as the mechanisms of glucagon and insulin secretion. At Lund University, I also participate in studies of animal models of type 2 diabetes.
Keywords
Insulin secretion / transcription factors / mitochondrial metabolism / intracellular calcium / signal transduction / glucagon secretion / gene expression