EMBO Member
University, Göteborg | Sweden
EMBO 2022
My laboratory is focused on studies of gene expression and DNA maintenance in mammalian mitochondria. We use in-vitro biochemistry, structural biology and and cell biology to study the underlying enzymatic processes. We also investigate the molecular consequences of disease-causing mutations affecting mitochondrial gene expression and develop new, rational therapeutic approaches.
Keywords: mtDNA / replication / transcription / RNA polymerase / mitochondrial disease
Subject area(s): Structural Biology & Biophysics | Molecular Medicine | Genome Stability & Dynamics | Chromatin & Transcription | Cellular Metabolism