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EMBO Member

Claire Rougeulle

Université Paris Diderot | France

EMBO 2016 | MemC 18–21

Long non-coding RNAs in development and disease

Our lab is interested in long-non-coding RNAs (lncRNAs) and their contribution to the regulation of gene expression in mammals, both in physiological and pathological contexts. We are mostly focusing on X chromosome inactivation, a paradigm for epigenetic regulations involving lncRNAs. We are also exploring, using cellular and animal models from various species, the plasticity of lncRNA function in evolution.

Keywords: Long non-coding RNAs / epigenetics / X-chromosome inactivation / stem cells / evolution

Subject area(s): Chromatin & Transcription | Development | RNA