
EMBO Member
Claudio E. Sunkel
EMBO 2000 | SciSocC 05–07 | WisC 08–12 | PolAG 12– | Council 17–19 | Council 20–22
Instituto de Investigação e Inovação em Saude (i3S), Porto, Portugal
Genomic stability during cell division
My laboratory is mostly devoted to the study of cell division and of the mechanisms involved in maintaining genomic stability in eukaryotes. I identified the Polo kinase, worked on gamma-tubulin, identified CLASPs and more recently studied checkpoint proteins like Mps1, Mad2, BubR1, Bu3 and CENP-E. Future research aims to further our understanding of the role of chromosome instability in tumorigenesis using Drosophila as model organism.
Keywords
Drosophila / mitosis / kinetochores / centrosomes / spindle / mitotic checkpoint / chromosome structure