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EMBO Member

Claudio E. Sunkel

Instituto de Investigação e Inovação em Saude (i3S), Porto | Portugal

EMBO 2000 | SciSocC 05–07 | WisC 08–12 | PolAG 12– | Council 17–19 | Council 20–22

Genomic stability during cell division

My laboratory is mostly devoted to the study of cell division and of the mechanisms involved in maintaining genomic stability in eukaryotes. I identified the Polo kinase, worked on gamma-tubulin, identified CLASPs and more recently studied checkpoint proteins like Mps1, Mad2, BubR1, Bu3 and CENP-E. Future research aims to further our understanding of the role of chromosome instability in tumorigenesis using Drosophila as model organism.

Keywords: Drosophila / mitosis / kinetochores / centrosomes / spindle / mitotic checkpoint / chromosome structure

Subject area(s): Cell Cycle | Cell & Tissue Architecture | Genome Stability & Dynamics