Instituto de Investigação e Inovação em Saude (i3S), Porto | Portugal
EMBO 2000 | SciSocC 05–07 | WisC 08–12 | PolAG 12– | Council 17–19 | Council 20–22
My laboratory is mostly devoted to the study of cell division and of the mechanisms involved in maintaining genomic stability in eukaryotes. I identified the Polo kinase, worked on gamma-tubulin, identified CLASPs and more recently studied checkpoint proteins like Mps1, Mad2, BubR1, Bu3 and CENP-E. Future research aims to further our understanding of the role of chromosome instability in tumorigenesis using Drosophila as model organism.
Keywords: Drosophila / mitosis / kinetochores / centrosomes / spindle / mitotic checkpoint / chromosome structure