Cellular dynamics during asymmetric cell division
My lab is studying asymmetric cell division (ACD), a process that generates cellular diversity. We are using neural stem cells in the fly as a model to investigate the molecular cell biology and mechanics of asymmetric stem cell division. To this end, we are focusing on the mechanisms underlying centrosome asymmetry and biased centrosome segregation. Furthermore, we are interested in actomyosin dynamics and mechanical forces underlying ACD.
Keywords
Asymmetric cell division / stem cells / cytokinesis / cell polarity / Drosophila