Cell and tissue dynamics during development
My group investigates the interactions between cell-cell signalling and critical cell behaviours that organise largescale tissue dynamics during multicellular morphogenesis of the social amoebae Dictyostelium discoideum and gastrulation in the chick embryos. We use molecular genetic and physico-chemical perturbations, live imaging and biophysical modelling to elucidate cellular properties and behaviours controlling emergent tissue dynamics.
Keywords
Chemotaxis / gastrulation / live imaging / cell-cell signalling / cytoskeleton / tissue morphogenesis / mathematical modelling