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EMBO Young Investigator

Daan Swarts

University, Wageningen | Netherlands

YIP 2023–2026

Function & mechanisms of bacterial immune systems

Research in the Swarts lab focusses on the functional, structural, and mechanistic characterization of protein complexes that control prokaryotic immunity. This includes prokaryotic Argonaute proteins, CRISPR-Cas systems, and more. These immune systems are not only interesting from fundamental biology and evolution perspectives, but also because they can be repurposed as tools for programmable genome editing or nucleic acid detection.

Keywords: Argonaute / CRISPR-Cas / prokaryotic immune systems / RNA interference / protein-nucleic acid interactions / evolution

Subject area(s): Microbiology, Virology & Pathogens | Proteins & Biochemistry | Structural Biology & Biophysics | Evolution & Ecology