University, Zurich | Switzerland
We use fission yeast and Drosophila embryos as model systems to study how cell type-specific architecture is set up and maintained, in order to provide either robust or dynamic cell shape and consequently cell type-specific function. For this we study the plethora of roles exerted by the actin and microtubule cytoskeletons, which together with associated proteins are the main organisers of cellular content.
Keywords: Tissue morphogenesis / cell architecture / cell polarisation / cytoskeleton organisation / cell force generation
Subject area(s): Cell & Tissue Architecture | Development | Structural Biology & Biophysics