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EMBO Member

Danijela Matic Vignjevic

Institut Curie, Paris | France

EMBO 2020

Cell migration in gut homeostasis and cancer

We are interested in how epithelial cells interact with their microenvironment, focusing on the extracellular matrix and fibroblasts in gut homeostasis and during cancer invasion. Our research strategy combines cell biology techniques with live-cell imaging using different model systems such as organoids, ex-vivo tissue slices, transgenic mouse models, and patient-derived fibroblasts.

Keywords: Cell migration / invasion / gut homeostasis / cancer-associated fibroblasts / microenvironment / mechanobiology / cytoskeleton / imaging

Subject area(s): Cell & Tissue Architecture | Molecular Medicine | Signal Transduction | Structural Biology & Biophysics

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