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EMBO Member

David Bensimon

École Normale Supérieure, Paris | France

EMBO 2011

From single molecule biophysics to single cell physiology

Our lab is studying biological systems from single molecules to organisms and evolution, using physical approaches (via both new experimental tools and models). Thus we study single DNA-protein interactions in-vitro using a magnetic trap system that we developed. We also investigate these issues in-vivo in single E. coli using single molecule fluorescence technique. We are also developing tools to control and observe cellular processes at the single cell level in a live organism. Finally, we study problems in bacterial evolution and ecology.

Keywords: Single molecule biophysics / single-cell physiology / optogenetics / evolution

Subject area(s): Development | Systems Biology | Evolution & Ecology