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EMBO Associate Member

David L. Spector

Cold Spring Harbor Laboratory | United States

EMBO 2014

Nuclear organization and gene expression

Research in my laboratory centers on elucidating the organization and regulation of gene expression. Our studies focus on implementing innovative approaches to examine spatial/temporal aspects of gene expression in mouse embryonic stem cells and other cell types. In addition, we are characterizing the role of long non-coding RNAs in breast cancer progression and differentiation.

Keywords: Cell nucleus / nuclear organization / non-coding RNAs / gene expression / breast cancer / live-cell imaging

Subject area(s): Chromatin & Transcription | RNA