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EMBO Member

Diego Pasini

European Institute of Oncology (IEO), Milano | Italy

EMBO 2021

Epigenetic control of transcriptional identity

The work of our laboratory is focused on the molecular mechanisms that regulate the establishment and maintenance of transcriptional identity in development, tissue homeostasis and regeneration. We concentrate on the role played by the chromatin environment and its modifications, characterising the activities involved and their underlying mechanisms of action, to define the impact of their deregulation in human diseases like cancer.

Keywords: Epigenetics / Polycomb / histone modifications / transcription / stem cells / differentiation / cancer

Subject area(s): Chromatin & Transcription | Development | Molecular Medicine