
EMBO Member
Dimitris Kioussis
EMBO 1997 | FelC 08–10
London, United Kingdom
Chromatin structure and lymphoid development
We are studying CD2 and CD8 gene expression during thymocyte development. We are identifying the chromatin structures established in expressing or non-expressing states of these genes. In other studies, we are investigating the cellular and molecular requirements for lymphoid organ formation by in vivo and in vitro imaging of specific lymphoid cell types expressing fluorescent proteins.
Keywords
Lymphocyte development & differentiation / gene expression / chromatin / T cell development / transgenic mice