EMBO Member
Dirk Bumann
EMBO 2015
Former EMBO Young Investigator (2007)
Biozentrum, Basel, Switzerland
Pathogen subpopulations in disease and control
Our group studies host-pathogen interactions for the three pathogens Salmonella, Shigella, and Pseudomonas. We are developing new single-cell approaches to detect, visualize, and purify pathogen subsets from distinct host micro-environments. Our results show an astonishing diversity of host-pathogen encounters in infected tissues with major implications for disease progression, antimicrobial treatment, and vaccine efficacy.
Keywords
Infection / bacterial pathogens / metabolism / heterogeneity / metabolism / vaccines