
The mechanism of nuclear pore complex and ribosome assembly
The research goal of our group is to understand how complicated macromolecular assemblies – the nuclear pore complex and the ribosomal subunits – are formed in the eukaryotic cell. To reach these goals we apply in vivo cell biology and genetic approaches, and in vitro biochemical and structural reconstitution.
Keywords
Nuclear pore complex / nucleo-cytoplasmic transport / nucleolus / ribosome biogenesis