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EMBO Member

Edward A. Lemke

Johannes-Gutenberg-Universität, Mainz | Germany

EMBO 2022 | FelC 24–

Synthetic biophysics of protein disorder

We are a multidisciplinary group of chemists, physicists, biologists and engineers interested in understanding molecular mechanisms that are driven by disorder. We develop biophysical tools to visualize molecular mechanisms in vitro and in living cells, and we innovate synthetic and chemical biology approaches to tune, control and study molecular and cellular processes in real time down to single-molecule resolution.

Keywords: Intrinsically disordered proteins / nuclear pore function & dynamics / super-resolution microscopy / single-molecule FRET / chemical biology / synthetic biology / condensates / non-natural amino acids

Subject area(s): Membranes & Transport | Proteins & Biochemistry | Structural Biology & Biophysics | Systems Biology