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EMBO Member

Elina Ikonen

University of Helsinki | Finland

EMBO 2019 | CouC 21–22

Lipid transport and storage in human cells

My group focuses on lipid transport and storage mechanisms relevant for human disease: cholesterol and sphingolipids accumulate in lysosomal lipidoses, cholesteryl esters are the storage form of excess cholesterol, and triglycerides the chemical storage form of excess energy. We study how the exchange of lipids between storage organelles, membranes and the extracellular environment is controlled in normal and diseased states.

Keywords: Cholesterol / membrane traffic / membrane domains / lipid droplets / lipid storage disease

Subject area(s): Cellular Metabolism | Membranes & Transport | Molecular Medicine