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EMBO Member

Elisabeth Knust

MPI für molekulare Zellbiologie und Genetik, Dresden | Germany

EMBO 1997

Apico-basal polarity in development and homeostasis

We are interested in the cellular, molecular and genetic mechanisms required for the maintenance of apico-basal polarity during development and homeostasis. These are particularly required in cells exposed to stress. This can be mechanical stress, taking place during morphogenesis of epithelial sheets. Light is a stress factor acting particularly on the photosensitive apical membrane of photoreceptor cells, which have to be renewed constantly.

Keywords: Drosophila / epithelial development / cell polarity / morphogenesis / retinal degeneration

Subject area(s): Cell & Tissue Architecture | Development | Differentiation & Death