Biology of human antigen-presenting cells
My lab studies the biology of antigen-presenting cells (dendritic cells, macrophages, monocytes) in health and pathology, and how they integrate signals from their environment. Our ultimate goal is to manipulate the properties of these cells for disease treatment, in particular cancer and inflammatory diseases. To achieve this, we combine studies of human cells isolated from tissues, in-vitro models using human cells, and in-vivo models in mouse.
Keywords
Human / monocyte / dendritic cell / macrophage / aryl hydrocarbon receptor