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EMBO Member

Emilio Hirsch

Università di Torino | Italy

EMBO 2015

Functional analysis of PI3K signaling

Our lab studies the function of PI3K enzymes in signal transduction. Currently our research focuses on the the role of class 1 and 2 PI3K isoforms in development, metabolism, and cancer. We also actively study kinase-dependent activity as well as kinase-independent scaffold functions of PI3K class 1 and 2, in cardiovascular pathology, airway diseases and cancer.

Keywords: Signal transduction / phosphoinositide 3-kinase / inflammation / phosphodiesterases / endocytic trafficking

Subject area(s): Membranes & Transport | Molecular Medicine | Signal Transduction