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EMBO Member

Emmanuelle Charpentier

MPI für Infektionsbiologie, Berlin | Germany

EMBO 2014

Regulatory RNAs and proteins in infection biology

We are interested in understanding how RNAs and proteins fine-modulate gene expression at the transcriptional, post-transcriptional and post-translational level in bacteria with a focus on human pathogens. We study signaling pathways that involve regulatory RNAs, CRISPR-Cas systems, Clp-mediated protein quality control, toxin-antitoxin systems in the interaction of bacteria with their environment (stress, mobile genetic elements and human host).

Keywords: CRISPR-Cas / regulatory RNAs / protein quality control / bacterial pathogens / innate immunity

Subject area(s): Immunology | Microbiology, Virology & Pathogens | RNA