
EMBO Member
Emmanuelle Charpentier
EMBO 2014
Max Planck Unit for the Science of Pathogens, Berlin, Germany
Regulatory RNAs and proteins in infection biology
We are interested in understanding how RNAs and proteins fine-modulate gene expression at the transcriptional, post-transcriptional and post-translational level in bacteria with a focus on human pathogens. We study signaling pathways that involve regulatory RNAs, CRISPR-Cas systems, Clp-mediated protein quality control, toxin-antitoxin systems in the interaction of bacteria with their environment (stress, mobile genetic elements and human host).
Keywords
CRISPR-Cas / regulatory RNAs / protein quality control / bacterial pathogens / innate immunity