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EMBO Member

Eran Meshorer

The Hebrew University, Jerusalem | Israel

EMBO 2025

Stem cell epigenetics and neuronal disease modeling

Our lab uses single-cell and genome-wide approaches to understand chromatin and epigenetic regulation in embryonic and neuronal stem cells, in reprogramming, and in human pluripotent models of neurodegenerative diseases, especially poly-glutamine (polyQ)-related disorders (e.g. Huntington's disease), as well as epigenetics of archaic genomes ('paleo-epigenetics'), a field which we co-pioneered.

Keywords: Chromatin / epigenetics / stem cells / paleo-epigenetics / neurodegenerative disease / disease modeling / pluripotency / organoids

Subject area(s): Chromatin & Transcription | Neuroscience | Evolution & Ecology

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