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EMBO Member

Erik Sahai

Francis Crick Institute, London | United Kingdom

EMBO 2014

Cancer invasion and the tumour microenvironment

My group is interested in understanding how cancer spreads through the body and how heterogeneous tumour microenvironments modulate the behaviour of cancer cells. To tackle these problems we use a range of techniques spanning computational modelling, conventional molecular and cell biology, organotypic cultures, intravital imaging of tumour models and primary culture of patient-derived tissue.

Keywords: Cell motility / intravital imaging / tumour microenvironment / metastasis / cancer-associated fibroblasts

Subject area(s): Cell & Tissue Architecture | Molecular Medicine | Signal Transduction