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EMBO Member

Eugenia Piddini

University, Bristol | United Kingdom

EMBO 2023

Mechanism and impact of cell competition on tissues

My group aims to understand how cell competition impacts on tissue colonization. We use Drosophila, mammalian cells in culture, genetics, omics and cell biology to investigate the mechanism of action of cell competition in health and disease. We aim to control tissue colonization outcomes for therapeutic applications, specifically to inhibit tissue colonisation of cancer cells and to promote tissue repopulation in regenerative medicine.

Keywords: Cell competition / tumour growth / oxidative stress / stem cells / ribosome gene mutations / cell interactions

Subject area(s): Cell & Tissue Architecture | Development | Molecular Medicine | Signal Transduction