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EMBO Associate Member

Eva Nogales

University of California, Berkeley | United States

EMBO 2019

CryoEM study of macromolecular structural dynamics

My lab is dedicated to the visualization of macromolecular function, using cryo-EM as a main experimental tool. We study the machinery involved in control of gene expression, as well as cytoskeleton interaction and dynamics in cell division. The unifying principle in our work is the study of macromolecular assemblies as whole units of molecular function by direct visualization of their architecture, functional states, and regulatory interactions.

Keywords: Eukaryotic transcription initiation / epigenetic silencing / microtubule dynamics / microtubule binding proteins / cryo-electron microscopy

Subject area(s): Cell & Tissue Architecture | Chromatin & Transcription | Proteins & Biochemistry | Structural Biology & Biophysics