EMBO Member
F. Ulrich Hartl
EMBO 1998
MPI für Biochemie, Martinsried, Germany
Role of molecular chaperones in health and disease
My lab is interested in the pathways and machineries of cellular protein folding and assembly. Our major focus is on the role of molecular chaperones in promoting folding and preventing aggregation. A second area of research concerns the mechanisms of cellular pathology in protein aggregation diseases, including neurodegenerative disorders such as Huntington's, Parkinson's and Alzheimer's disease.
Keywords
Mechanism of folding in the cell / structure & function of heat shock proteins & molecular chaperones / neurodegenerative diseases of protein misfolding & aggregation