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EMBO Member

Fanni Gergely

University of Oxford | United Kingdom

EMBO 2019

Centrosomes in mitosis, development and disease

My group seeks to understand how centrosomes contribute to normal and pathological processes such as embryonic growth, neurodevelopment and tumourigenesis. We use a combination of genetic, molecular and proteomic tools to interrogate the roles of centrosome components in cell proliferation and signalling. Our current work focuses on identifying tissue- and cell type-specific functions for these ubiquitous organelles.

Keywords: Mitosis / centrosome / microtubules / microcephaly / cell cycle / neurodevelopment / chromosome segregation

Subject area(s): Cell Cycle | Cell & Tissue Architecture | Genome Stability & Dynamics | Molecular Medicine