Institute for Research in Biomedicine, Bellinzona | Switzerland
We combine ex vivo analysis of memory T lymphocytes with in vitro priming experiments to understand the mechanisms that control T cell commitment to different fates and the co-regulation of effector functions and migratory capacities. In parallel, we use the mouse system to address fundamental questions in the regulation of lymphocyte trafficking in immunity and autoimmunity.
Keywords: T lymphocytes / cytokines / immunological memory / lymphocyte migration / chemokine receptors
Subject area(s): Immunology