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EMBO Member

Francesco Cecconi

Danish Cancer Research Center, Copenhagen | Denmark

EMBO 2012 | FelC 17–22

My lab is involved in the dissection of the molecular pathways regulating autophagy during vertebrate development and in a number of pathological conditions. In this context, we aim at unravelling the mechanisms of autophagosome formation and its cross-talk with both apoptosis and the cell cycle machinery. Also, we work on the molecular network regulating synaptic degeneration and involving non-apoptotic roles for death-related molecules.

Keywords: Apoptosis / autophagy / mitochondria / signalling / ubiquitin

Subject area(s): Differentiation & Death | Membranes & Transport | Molecular Medicine | Neuroscience | Proteins & Biochemistry