Danish Cancer Research Center, Copenhagen | Denmark
EMBO 2012 | FelC 17–22
My lab is involved in the dissection of the molecular pathways regulating autophagy during vertebrate development and in a number of pathological conditions. In this context, we aim at unravelling the mechanisms of autophagosome formation and its cross-talk with both apoptosis and the cell cycle machinery. Also, we work on the molecular network regulating synaptic degeneration and involving non-apoptotic roles for death-related molecules.
Keywords: Apoptosis / autophagy / mitochondria / signalling / ubiquitin
Subject area(s): Molecular Medicine | Neuroscience | Proteins & Biochemistry | Membranes & Transport | Differentiation & Death