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EMBO Member

François Schweisguth

Institut Pasteur, Paris | France

EMBO 2012

Cell fate and morphogenesis in Drosophila

We study how individual cells acquire and change identity, shape and function and thereby build and maintain functional tissues and organs during development. We use genetic/genomic, cellular/molecular, imaging and computational approaches to investigate several developmental processes in Drosophila. In particular, we investigate the regulation of Delta-Notch signalling and epithelial polarity remodelling with a specific focus on asymmetric cell division.

Keywords: Cell polarity / Drosophila / Notch / asymmetric cell division / endocytosis / morphogenesis / patterning

Subject area(s): Cell & Tissue Architecture | Development | Signal Transduction