EMBO Member
Frank Bradke
EMBO 2013
Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany
Axon growth and regeneration
Research in our lab has focused on the intracellular mechanisms regulating axon growth during development and after injury with a particular emphasis onto the cytoskeleton. We found that the intracellular mechanisms mediating axon growth during development share similarities with the ones that regulate axon regeneration. The ultimate aim is to reactivate the polarization program in injured neurons to elicit axon regeneration in the CNS.
Keywords
Axon growth / neuronal polarity / axon regeneration / cytoskeleton