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EMBO Member

Frank Uhlmann

Francis Crick Institute, London | United Kingdom

EMBO 2006 | CouC 09–12 | CouC 13–16 | PubAB 13–17 | EEsC 14–16

Chromosome structure and segregation

The aim of the Chromosome Segregation Laboratory is to investigate cellular mechanisms that safeguard accurate chromosome segregation. We are investigating the contribution of structural chromosomal proteins to the faithful segregation of the centimetre-long chromosomal DNA molecules within micrometre-sized cells. A second topic of our research is the regulation of ordered mitotic progression by the cell division cycle machinery.

Keywords: Cell cycle / mitosis / chromosome structure & segregation / SMC protein complexes

Subject area(s): Cell Cycle | Genome Stability & Dynamics | Systems Biology