EMBO Member
Geneviève de Saint Basile
EMBO 2009
Hôpital Necker, Paris, France
Normal and pathological immune homeostasis
Our main research interests are the development and the homeostasis of the immune system. Current research activities are focused on the role of the cytotoxic activity in the regulation of lymphocyte homeostasis, and the mechanism by which inappropriate RhoA kinase activity impairs immune and gut epithelial homeostasis, through the studies of inherited deficiencies.
Keywords
Homeostasis of the immune system / cytotoxic activity / exocytosis / inherited immune disorder / vesicle trafficking / murine models