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EMBO Member

Geneviève de Saint Basile

Hôpital Necker, Paris | France

EMBO 2009

Normal and pathological immune homeostasis

Our main research interests are the development and the homeostasis of the immune system. Current research activities are focused on the role of the cytotoxic activity in the regulation of lymphocyte homeostasis, and the mechanism by which inappropriate RhoA kinase activity impairs immune and gut epithelial homeostasis, through the studies of inherited deficiencies.

Keywords: Homeostasis of the immune system / cytotoxic activity / exocytosis / inherited immune disorder / vesicle trafficking / murine models

Subject area(s): Immunology | Membranes & Transport | Molecular Medicine