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EMBO Member

George Kollias

BSRC Alexander Fleming, Vari | Greece

EMBO 2000 | MemC 06–09

Mechanisms of chronic inflammation

We aim to understand the molecular and cellular mechanisms underlying chronic inflammatory and autoimmune diseases, and to develop innovative tools for diagnosis, prognosis and therapy. We combine large scale approaches with in depth dissection of gene function in vivo and in vitro, from human vs animal models, to discover causalities in the epigenetic, biochemical, molecular and cellular changes that occur along disease progression.

Keywords: Animal models / chronic inflammation / innate immunity / cytokines / TNF / genomics / mesenchymal cells

Subject area(s): Immunology | Molecular Medicine | Signal Transduction