EMBO Associate Member
Johns Hopkins University, Baltimore | United States
We study how single-cell embryos localize RNAs and proteins to pattern developmental potential. We use genetics, microscopy and biochemistry to identify, observe and manipulate RNAs and proteins in and out of cells. Most recently, my group has identified a class of intrinsically-disordered proteins that regulate the formation and localization of germ granules, RNA granules in germ cells.
Keywords: Cell polarity / C. elegans / germ cells / RNA granules
Subject area(s): RNA | Differentiation & Death | Development | Cell & Tissue Architecture