University of Basel | Switzerland
EMBO 2000 | MemC 09–12 | YipC 17–20
My laboratory employs cultured cancer cell lines and refined mouse models of carcinogenesis to delineate the molecular mechanisms underlying malignant tumor progression and metastasis formation. One major focus is the transcriptional and epigenetic control of epithelial-mesenchymal transition (EMT) during tumor progression. Another focus is the molecular mechanisms underlying the development of resistance against targeted cancer therapy.
Keywords: Tumour biology / angiogenesis / invasion / metastasis / transgenic & knockout mice
Subject area(s): Molecular Medicine