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EMBO Member

Giampietro Schiavo

University College London | United Kingdom

EMBO 2010 | InstgC 22–25

Axonal transport in neurodegenerative diseases

Our research is focussed on elucidating the mechanism controlling axonal transport, a process that functionally connects distal compartments of a neuron, such as synapses, with events occurring in the cell body. Our findings demonstrated that defects in axonal transport constitute a major pathogenic mechanism in neurodegenerative disorders.

Keywords: Axonal transport / molecular motors / motor neuron disease / neurotrophin / membrane traffic

Subject area(s): Membranes & Transport | Molecular Medicine | Neuroscience