EMBO Member
Giannino Del Sal
EMBO 2006
International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy
Pathways and networks in cancer and other diseases
With both basic and translational approaches to molecular oncology, my group is mainly focused on the mechanisms of tumor initiation and progression, with a long lasting commitment to the study of the p53 oncosuppressor and its neighbourhood, to the dissection of wt/mut p53 and other oncogenic pathways' regulatory networks, primarily in cancer development and metastasis, but also in other pathological conditions such as neurodegenerative diseases.
Keywords
Cancer / metastasis regulators / cancer stem cells / EMT / cancer cell metabolism