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EMBO Member

Giannino Del Sal

International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste | Italy

EMBO 2006

Pathways and networks in cancer and other diseases

With both basic and translational approaches to molecular oncology, my group is mainly focused on the mechanisms of tumor initiation and progression, with a long lasting commitment to the study of the p53 oncosuppressor and its neighbourhood, to the dissection of wt/mut p53 and other oncogenic pathways' regulatory networks, primarily in cancer development and metastasis, but also in other pathological conditions such as neurodegenerative diseases.

Keywords: Cancer / metastasis regulators / cancer stem cells / EMT / cancer cell metabolism

Subject area(s): Cellular Metabolism | Molecular Medicine | Signal Transduction