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EMBO Member

Gioacchino Natoli

European Institute of Oncology (IEO), Milano | Italy

EMBO 2013 | CouC 23–26

Genomic regulation of inflammation

My current research activity is mainly focused on the transcriptional and chromatin-mediated control of inducible gene expression in inflammatory responses. We are investigating how the integration of cell intrinsic and environmental cues at genomic cis-regulatory elements specifies transcriptional outputs. More recently we started characterizing transcriptional mechanisms that control differentiation in human pancreatic cancer

Keywords: Macrophages / inflammation / transcription / chromatin / genomics / pancreatic cancer

Subject area(s): Chromatin & Transcription | Genomic & Computational Biology | Immunology