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EMBO Member

Giovanni Marsicano

Neurocentre Magendie, Bordeaux | France

EMBO 2019

The endocannabinoid system: a path to brain complexity

The research of my lab fits a clear 'bottom-up' approach. Studying the signalling of cannabinoid CB1 receptors, we recently contributed to the identification of key mechanisms regulating brain functions and behavior, such as the fine-tune balance between excitation and inhibition in specific circuits, the roles of astrocytes in memory, and the impact of mitochondrial bioenergetic processes on neuronal and astroglial signalling.

Keywords: Cannabinoid / neuron / synapse / behavior / mitochondrion / astrocytes / pregnenolone / pharmacology / physiology

Subject area(s): Cellular Metabolism | Membranes & Transport | Neuroscience | Signal Transduction