
EMBO Member
Giovanni Marsicano
EMBO 2019
Neurocentre Magendie, Bordeaux, France
The endocannabinoid system: a path to brain complexity
The research of my lab fits a clear 'bottom-up' approach. Studying the signalling of cannabinoid CB1 receptors, we recently contributed to the identification of key mechanisms regulating brain functions and behavior, such as the fine-tune balance between excitation and inhibition in specific circuits, the roles of astrocytes in memory, and the impact of mitochondrial bioenergetic processes on neuronal and astroglial signalling.
Keywords
Cannabinoid / neuron / synapse / behavior / mitochondrion / astrocytes / pregnenolone / pharmacology / physiology